Confocal microscopic images of <i>Streptococcus pneumoniae</i> D39 biofilms grown with and without pyrimidinedione.

<p><b>(</b>A & B) Representative confocal images of a control sample. The biofilms in the control sample were thick with an organized 3-dimesional structure. <b>(</b>C & D) Representative confocal images of biofilms grown with 7 μM/ml pyrimidinedione. The pyrimidinedione-grown biofilms were thin and disorganized, with clumps of cells attached to the bottom of plate.</p>