“Conditional Manhattan plot” of conditional −log10 (FDR) values for Bipolar disorder (BD) alone (black) and BD given schizophrenia (SCZ; BD|SCZ, blue).

SNPs with conditional −log10 FDR>1.3 (i.e. FDR<0.05) are shown with large points. A black line around the large points indicates the most significant SNP in each LD block and this SNP was annotated with the closest gene, which is listed above the symbols in each locus. The figure shows the localization of significant loci. Details about the loci are provided in Table 2.