Figure_1.tif (3.14 MB)
CaMKII is present in the guinea pig ENS.
figure
posted on 2012-08-31, 00:53 authored by Na Gao, Jialie Luo, Karen Uray, Aihua Qian, Shijin Yin, Guodu Wang, Xiyu Wang, Yun Xia, Jackie D. Wood, Hongzhen Hu(A) Representative Western Blot analysis reveals the presence of CaMKII-IR in protein extracts of guinea pig myenteric and submucosal plexuses of both ileum and colon. p-CaMKII-IR was also present in the myenteric plexus. Calbindin (28 kD) which is only expressed by enteric neurons was used as a positive control. (B & C) Low magnification images illustrate that many guinea pig ileal myenteric neurons had CaMKII-IR. (D) CaMKII-IR was exclusively expressed by uniaxonal S-type myenteric neurons and present in both cell soma and nerve fibers. Bar = 20 μm.
