CLUSTAL 2.1 multiple sequence alignment of diphospho mevalonate decarboxylases from Brugia malayi (BmMVD), Loa loa (LlMVD), Homo sapiens (HsMVD) and Saccharomyces cerevisiae (ScMVD), highlighting two regions in the published BmMVD sequences that diverge from the consensus between the orthologous protein sequences.

These could be due to the presence of different splice variants of the Brugia enzyme, natural insertions or errors in the published sequence.* conserved residues;: chemically conserved changes;. non-conserved changes.