CCND1 and RSF-1 gene amplification by FISH.
Images (100X magnification) of FISH for CCND1 (A) and RSF-1 (B) on two different breast tumor samples from the MA.12 tissue microarray. Sample A shows CCND1 gene amplification while sample B shows RSF-1 amplification. Green dots are centromeric probes for chromosome 11, while red dots represent the gene probes. Counterstaining is with DAPI II.