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BmCRT prevent C1q-dependent haemolysis of Ig-sensitized erythrocytes.

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posted on 2014-09-03, 03:08 authored by Sunita Yadav, Smita Gupta, Chandrabose Selvaraj, Pawan Kumar Doharey, Anita Verma, Sanjeev Kumar Singh, Jitendra Kumar Saxena

Recombinant BmCRT inhibits C1q-dependent haemolysis while BSA (control) shows no effect on this when incubated with C1q deficient serum together with C1q as described in material and method section. Percentage of cell lysis was calculated with reference to 100% lysis of the cells in water. The significant were analyzed by two-way ANOVA (***P<0.001). Assay was performed in triplicates. Bar represent the standard deviations of the mean.

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