Bacteria and spore burden in the lungs of mice.
Average retained dose was determined by harvesting the lungs 1 hour after intranasal inoculation and dilution plating the lung homogenates.b
The amounts of total bacteria and spores in the lung as described in the Figure 1 legend are expressed as the mean±SEM at 2, 4, or 8 weeks post-inoculation. Results are combined from two independent experiments.c
Statistical analysis was performed using the two-tailed Student's t-test. *, p<0.05; **, p<0.01; compared to respective total bacteria and spore titers at 2 weeks.d