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Analysis of ribosome occupancy and ribosome density in HEK293T cells.

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posted on 2009-11-10, 01:50 authored by David G. Hendrickson, Daniel J. Hogan, Heather L. McCullough, Jason W. Myers, Daniel Herschlag, James E. Ferrell, Patrick O. Brown

(A) The number of genes as a function of ribosome occupancy. The average ribosome occupancy is 85%. (B) The number of genes as a function of ribosome density. On average, there is one ribosome per 189 nucleotides. (C) Ribosome density as a function of a gene's coding sequence length. Each gene is indicated by a blue circle. The red line indicates the moving average density value (window of 50). The inset shows only genes with coding sequences that are shorter than 1,000 nucleotides.

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