Figure_1.tif (2.2 MB)
Alignment of peptide sequences of Torpedo AChE, Human BChE, Medaka (O. latipes) AChE and Atypical BChE.
figure
posted on 2011-02-25, 01:25 authored by Leo Pezzementi, Florian Nachon, Arnaud ChatonnetNumbering of the amino acid sequences is indicated on the right and starts with the amino acids of the mature polypeptide. Conserved (*) and similar (:.) residues are indicated. Locations of the three elements of the catalytic triad are indicated (•). Single underlines link the cysteines participating in intrachain disulfide bond. Sites of conserved aromatic amino acids lining the catalytic gorge in AChE are indicated with↓or↑; those not conserved in medaka (O. latipes) atypical BChE are marked with↑.