Treatment with allopurinol for 12 weeks was not associated with increased expression of 1α- hydroxxylase protein compared to placebo (p value for generalized linear mixed model = 0.59).

The figures represent change in the expression of the protein from baseline by study group. Values for each sample were reported as arbitrary units and represent ratios of endothelial cell protein expression to human umbilical vein endothelial cell (HUVEC) expression in order to account for any variation in the staining procedure.