The performance of different algorithms in predicting the CDR of patients using models trained on preclinical CCL samples.

The second column shows the properties of the algorithm (linear versus nonlinear; single task versus multi-task learning). The third column shows the number of drugs for which a statistically significant discrimination between resistant and sensitive patients was obtained (one-sided Mann Whitney U test). The fourth column shows the total number of drugs included in the evaluation, and the fifth column shows the combined p-value (using Fisher’s method) for all the drugs in the analysis.