The MrBayes majority-rule consensus tree reveals a distinct phylogenetic relationship between Cryptococcal Mpr1 and other M36 family members.

The MrBayes tree is based on ClustalW2 amino acid sequence alignments of CnMPR1 and other M36 family members and obtained from searching the HMMER web server (hmmer.janelia.org). The Bayesian tree reveals a distinct phylogenetic relationship between Mpr1 in Cryptococcus species and M36 family members in other fungi. An Mpr1 homolog was identified in the closely related basidiomycete Tremella mesenterica, however, Mpr1 clusters separately from the rest of the M36 family. Posterior probability values are shown as node labels. Well supported nodes indicated by a “1” with maximum likelihood bootstrap (BS) support >80.