The MAPK signaling pathways in the kidneys of mice with AAI-induced acute nephropathy.

The expression of p-REK1/2 (A), p-JNK (B) and p-38 (C) in kidney tissue was determined using Western blotting, and representative results of Western blotting are shown (D). All values are expressed as the means ± SD from each group (n = 9). * and ** indicate p < 0.05 and p < 0.01 compared to the Control group, respectively; † and †† indicates p < 0.05 and p < 0.01 compared to the AAI group, respectively.