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Structures of Y₄R PAMs identified by HTS and inactive control compounds chosen for further characterization of Y₄R PAM activity and YR subtype selectivity.

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posted on 2016-06-13, 08:08 authored by Gregory Sliwoski, Mario Schubert, Jan Stichel, David Weaver, Annette G. Beck-Sickinger, Jens Meiler

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allosteric modulators increase Y 4 R activity scaffold Y 1 R molecule allosteric modulators Human Y 4 Receptor neuropeptide Y 4 receptor compound Y 5 R Y 4 R Y 2 R

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Structures of Y4R PAMs identified by HTS and inactive control compounds chosen for further characterization of Y4R PAM activity and YR subtype selectivity.

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Structures of Y₄R PAMs identified by HTS and inactive control compounds chosen for further characterization of Y₄R PAM activity and YR subtype selectivity.