Fig 1.tif (1.89 MB)
Structure of the cytoplasmic segment of the AC5 isoform of adenylyl cyclase in complex with ATP and the activating G-protein Gsα viewed from the side closest to the cell membrane.
figure
posted on 2018-04-25, 17:39 authored by Elisa Frezza, Juliette Martin, Richard LaveryThe C1 and C2 subunits of AC5 are colored blue and red respectively and Gsα is colored green. ATP is shown in a CPK representation with standard chemical coloring. A close-up view of the helix-helix interactions between AC5 and Gsα is provided (circle).