Figure_3.tif (726.85 kB)
Six month-old male whole body glucose, insulin and pyruvate tolerance.
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posted on 2014-02-10, 03:23 authored by Michelle L. Van Sinderen, Gregory R. Steinberg, Sebastian B. Jørgensen, Sarah Q. To, Kevin C. Knower, Colin D. Clyne, Jane Honeyman, Jenny D. Chow, Kerrie A. Herridge, Margaret E. E. Jones, Evan R. Simpson, Wah Chin BoonWhole body tolerance tests were completed on fasted 6 month-old male wildtype (WT), aromatase knockout (KO) and 2.5 µg/kg 17β-estradiol-treated KO (KOE). (a) Glucose tolerance test and corresponding area under curve; (b) insulin tolerance test and corresponding area under curve; (c) pyruvate tolerance test and corresponding area under curve. Data are presented from replicate analysis (n = shown on corresponding bar) as the mean ± SD. *p<0.05, **p<0.01, versus expression in age-matched WT samples and #p<0.05 and ##p<0.01 versus KO samples
