Fig 4.tif (214.4 kB)
Serum biochemical parameters of naïve BALB/c mice receiving ArtinM.
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posted on 2017-10-30, 17:39 authored by Patrícia Kellen Martins Oliveira Brito, Thiago Eleutério Gonçalves, Fabrício Freitas Fernandes, Camila Botelho Miguel, Wellington Francisco Rodrigues, Javier Emílio Lazo Chica, Maria Cristina Roque-Barreira, Thiago Aparecido da SilvaThe serum levels of CPK (A), CK-MB (B), GOT (C), GPT (D), alkaline phosphatase (E), urea (F), total protein (G), albumin (H), and globulin (I) were determined in samples harvested at day 0 from mice that received ArtinM at the specified dose (x axis). PBS and LPS was administered to the negative and positive controls, respectively. Results are expressed as mean ± SD, and differences were considered significant when p < 0.05 (*) compared to the PBS control group.
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Th 1 axiscreatine kinase MB isoenzymeArtinM-injected miceLPSimmunomodulatory doseROR -γtTNFIL -10 levelIFNserum levelsGATAplant lectinsantigen-presenting cellslectin ArtinMTLR 2 N-glycansT helperintracellular pathogensIL -12 production5.0 μ g ArtinMArtocarpus heterophyllusB cellsbody weightBALBSystemic effectsArtinM administrationCK-MBIL -10 measurementslung homogenatesimmunomodulatory effectimmunomodulatory lectin ArtinM Toll-like receptorsPBS-injected animals
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