Seasonal and monthly variation in the occurrence of Guillain-Barré syndrome (GBS).

The incidence of GBS of pediatric patients in spring, summer, autumn and winter was 13.9%, 51.7%, 24.9% and 9.6%, respectively. Accordingly, it was 24.4%, 36.2%, 24.0% and 15.3%, respectively, in the adult ones (A). Further, the monthly variation in the occurrence of GBS was investigated. The incidence of GBS in children and adult during January to December was 2.4% and 7.6%, 3.3% and 2.4%, 3.8% and 7.8%, 2.9% and 7.6%, 7.2% and 9.1%, 8.6% and 10.0%, 23.4% and 16.1%, 19.6% and 10.2%, 10.5% and 8.5%, 6.2% and 8.7%, 8.1% and 6.8%, 3.8% and 5.4%, respectively (B). In addition, the incidence of antecedent infections in spring, summer, autumn and winter was 64.0%, 64.3%, 66.3% and 68.6%, respectively, in adults with GBS; similarly, it was 72.4%, 60.2%, 70.6% and 65%, respectively, in pediatric GBS (C).