Fig 1.tif (419.93 kB)
SNPs analyzed in the A3F gene.
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posted on 2016-03-04, 07:24 authored by Ping An, Sudhir Penugonda, Christian W. Thorball, Istvan Bartha, James J. Goedert, Sharyne Donfield, Susan Buchbinder, Elizabeth Binns-Roemer, Gregory D. Kirk, Wenyan Zhang, Jacques Fellay, Xiao-Fang Yu, Cheryl A. Winkler(A) Gene structure and SNP locations. The colored blocks indicate exons, empty blocks, untranslated regions (UTR), horizontal arrows, the direction of transcription and vertical arrows, the positions of SNPs. (B) Linkage disequilibrium matrix of SNPs in the A3F gene region in European Americans, as illustrated by Haploview [74]. Red block indicates D’ = 1.0, and the number in the blocks indicates the value of D’. The linkage disequilibrium block depicted by black triangle was based on the 95% Confidence interval criteria. (C) Haplotypes in the A3F gene region in European Americans.
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pneumocystis pneumonia3F degradationRHresistance factorsAPOBEC 3FRelative HazardsSNPdegrades APOBEC 3 proteins3F proteinPCP3Gassociation studyInternational Collaborationinfectivity factorvalidation studyAIDSPneumocystis Pneumonia Human APOBEC 3 cytidine deaminasesCIICGHDisease Progression231V varianthost susceptibilityAPOBEC 3F Gene VariationVif degradationHIVEuropean Americans3F genedisease progression
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