Results from in vivo tests carried out in mice: Histological analysis and quantification of blood vessels in the tissues surrounding the implants.

Histological analysis by hematoxylin and eosin staining of PU and PU-LN1 scaffolds and surrounding tissues explanted 15 (A) and 30 (B) days following subcutaneous implantation in mice. Arrows indicate blood vessels (scale bar: 50 μm). (C) Number of blood vessels per mm2 in the tissues surrounding PU and PU-LN1 scaffolds, and explanted 15 and 30 days after subcutaneous implantation in mice. Unpaired two-tailed t test was used for statistical analysis.