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Results from in vivo tests carried out in mice: Histological analysis and quantification of blood vessels in the tissues surrounding the implants.

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posted on 2018-07-06, 17:41 authored by Monica Boffito, Franca Di Meglio, Pamela Mozetic, Sara Maria Giannitelli, Irene Carmagnola, Clotilde Castaldo, Daria Nurzynska, Anna Maria Sacco, Rita Miraglia, Stefania Montagnani, Nicoletta Vitale, Mara Brancaccio, Guido Tarone, Francesco Basoli, Alberto Rainer, Marcella Trombetta, Gianluca Ciardelli, Valeria Chiono

Histological analysis by hematoxylin and eosin staining of PU and PU-LN1 scaffolds and surrounding tissues explanted 15 (A) and 30 (B) days following subcutaneous implantation in mice. Arrows indicate blood vessels (scale bar: 50 μm). (C) Number of blood vessels per mm2 in the tissues surrounding PU and PU-LN1 scaffolds, and explanted 15 and 30 days after subcutaneous implantation in mice. Unpaired two-tailed t test was used for statistical analysis.

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