Response to energy stress in E2f7/8-deficient pancreas.

(A) Immunostaining for insulin and glucagon under fed conditions in mice injected with tamoxifen at the age of 1 week and analysed at the age of 22 weeks. (B) Immunostaining of insulin and glucagon after 4hrs of starvation. (C-F) Serum biochemical parameters under normal feeding conditions. (G-J) Serum biochemical parameters following 4hrs of starvation. Bar graphs represents average and standard error, *p<0.05.