Fig 2.TIF (1.51 MB)
Recap three-dimensional brain models showing the regions of interest (ROI) activated by chronic consumption of sugar-enriched diets.
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posted on 2016-09-01, 04:54 authored by Melissa Ochoa, Charles-Henri Malbert, Paul Meurice, David Val-Laillet3D-representations of the ROI that were significantly activated by both glucose and fructose compared to starch group (Starch < Glucose and Starch < Fructose), using the SPM8 (statistical parametric mapping) small volume correction (SVC) analysis (Punc < 0.001; Threshold T = 6.3). APFC, anterior prefrontal cortex; DLPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex; CAU, caudate nucleus; PUT, putamen. There was no statistical difference between glucose and fructose groups.
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reward-related brain regionsbasal brain metabolisminsulin sensitivitydorsolateral prefrontal cortexAdult Yucatan Minipigs Excessive sugar intakeinsulin sensitivity index7- month diet treatmentUIISIbody weightbasal brain glucose metabolism7- month intakebrain sugar transporterbrain activityreward-related brain areas18 FDG PET brain imaging
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