RIG-I expression.

RIG-I showed a localization pattern very similar to MDA-5 after the immunostaining of lung sections from never smokers (A) and very severe COPD patients (B). Additionally, non-COPD and COPD patients showed similar significant differences in both the immunostaining score (C) of respiratory epithelium and the mRNA expression (D). The upper bar indicates the differences between non-COPD patients and COPD patients.