Fig 5.TIF (1.03 MB)
Protein for both PAR1 and Par3 is undetectable in platelets from hPAR1-KI mice.
figure
posted on 2016-10-27, 17:42 authored by Shauna L. French, Antonia C. Paramitha, Mitchell J. Moon, Ross A. Dickins, Justin R. HamiltonWhole cell lysates of platelets isolated from hPAR1-KI mice, wild type mice, or humans were probed for either PAR1 or Par3 protein by Western blot. PAR1 was readily detected in human platelets but not in platelets from wild type or hPAR1-KI mice. In the same samples, Par3 was detected in platelets from wild type mice but not in platelets from either hPAR1-KI mice or humans. Actin was used as a protein loading control for all lysates. Blots shown are representative of n = 3 experiments.
History
Usage metrics
Categories
Keywords
platelet thrombin receptorsPAR 1 antagonisthPAR 1-KI miceMouse Platelets Anti-platelet drugsPAR 1 Expressionplatelet PAR functionPAR 1 expressionectopic PAR 1 expressionPAR expression profilehPAR 1-KI mouse plateletsmouse Par 3 locusHEK 293T cellsPar 3 LocusPAR 4 antagonistsPar 3 expressionPAR 1-activating peptidesurface P-selectin expressionPAR 1Knocking PAR 1
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC