Public Library of Science
Browse
Fig 11.tif (862.26 kB)

Proposed mechanism for the conjugation of catechol moiety of piceatannol to a nucleophilic thiol group (Cys149) in GAPDH molecule.

Download (862.26 kB)
figure
posted on 2018-01-03, 18:39 authored by Joanna Gerszon, Eligiusz Serafin, Adam Buczkowski, Sylwia Michlewska, Jakub Antoni Bielnicki, Aleksandra Rodacka

Proposed mechanism for the conjugation of catechol moiety of piceatannol to a nucleophilic thiol group (Cys149) in GAPDH molecule.

History

Usage metrics

    PLOS ONE

    Categories

    Keywords

    oxidative modificationsnucleophilic cysteine residueglyceraldehyde -3-phosphate dehydrogenase Glyceraldehyde -3-phosphate dehydrogenaseGAPDH aggregation11 ligand binding positionsITCGAPDH piceatannol blocks cysteine residuepiceatannol decreases GAPDH activityreactive cysteine residue

    Licence

    CC BY 4.0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC