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Principal component analysis (PCA) of wild-type BDNF and its variant V66M.

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posted on 2019-04-18, 17:43 authored by Clara Carolina Silva De Oliveira, Gabriel Rodrigues Coutinho Pereira, Jamile Yvis Santos De Alcantara, Deborah Antunes, Ernesto Raul Caffarena, Joelma Freire De Mesquita

The plots are showing the first two principal components (PC1 and PC2) extracted from the essential dynamics. The trajectory frames for wild-type BDNF and its variant V66M were colored from blue to red according to time evolution. (A) PCA plot of wild-type BDNF. The first two PCs account for 59.24% of the total structural variance. (B) PCA plot of variant V66M. The first two PCs account for 50.67% of the total structural variance. (C) PCA comparison between wild-type BDNF (black) and its variant V66M (blue).

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