Pressure-overload induced concentric hypertrophy and reactive fibrosis.

<p>(<b>Panel A)</b> Left ventricular (LV) wall thickness, circumference, <b>(Panel B</b>) interstitial and perivascular fibrosis as determined by Masson Trichrome staining were significantly increased in suprarenal abdominal aorta constricted rats (SAC) versus sham rats. Analysis was performed on a subpopulation of SAC (n = 3) and sham (n = 4) rats and (*) denotes <i>p</i><0.05 versus sham as determined by a student’s unpaired t-test.</p>