Fig 4.tif (76.67 kB)
Performance comparison between NG-motif, NGOME and our structure-based methods.
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posted on 2017-07-21, 17:37 authored by Lei Jia, Yaxiong SunNG-motif and NGOME prediction performances were represented by plotting the TPR v.s. FPR points (red triangle for NG-motif and blue square for NGOME) on the ROC of the RF method (purple line).
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3 D structure-based propertiesdata sets194 Asn residuesforest modelcauses over-engineeringdrug discovery processProtein asparagine deamidation predictionprediction toolshotspot residuestest datadeamidation casedeamidation half-lifeNG motifSequence-based prediction methodsequence-based methodmethods Chemical stabilityprotein therapeuticsstructure-based prediction modelsprediction methodacid residuesacid asparaginedihedral anglesprediction modelsdeamidated residues25 proteinsdeamidated proteinschemical modificationscrystal structuresprotein hotspot predictionstrain prediction modelsdeamidation evaluation processnon-deamidated residues
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