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OSU53 is more efficient than other known AMPK activators in protecting OB-6 cells against Dex.

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posted on 2016-09-15, 17:49 authored by Dawei Xu, Wei Zhao, Xinhui Zhu, Jianbo Fan, Shengyu Cui, Yuyu Sun, Xiang Chen, Wei Liu, Zhi-ming Cui

OB-6 cells were pretreated with OSU53 (10 μM), A-769662 (“A7”, 10 μM) or Compound 13 (“C13”, 10 μM) for 1 hour, followed by Dex (1 μM) stimulation for 24 hours, cell viability (MTT assay) was shown (A). Experiments in this figure were repeated three times, and similar results were obtained. *p<0.05 vs. “Dex” only treatment. # p<0.05 vs. OSU53 treatment group.

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