Fig 6.tif (3.69 MB)
Morphological changes in A549 cells stained with acridine orange (AO) and ethidium bromide (EB).
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posted on 2018-03-14, 17:38 authored by Mouadh Mihoub, André Pichette, Balla Sylla, Charles Gauthier, Jean LegaultCells were untreated (A) or treated for 3 h with 1 μM staurosporine (B), 10 μM β-hederin (C), 5 μM Bi-L-RhamBet (D), 10 μM Bi-L-RhamBet (E), and 20 μM Bi-L-RhamBet (F). A549 cells were stained with AO/EB for 5 min and then visualized using fluorescence microscopy. Arrows indicate apoptotic blebbing. This analysis is representative of three independent experiments.
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mitochondrial electron transfer chainROSNCI-HLLCIC 50 valuestumor growth inhibition rateETCBi-L-RhamBetapoptotic cell deathBidesmosidic betulin saponinlung cancer cell lines549 lung cancer cell linelung cancer cells growthDNApyruvate dehydrogenase kinase inhibitor potentiatedmitochondrial electron transport chain28- O -α- l549 cells
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