Micro colonisation of IMR-32 tumours in the PSCT model.

(A) Schematic illustration; NB cells were injected into an arbitrary position centrally in the PSCT cellular mass, resulting in multiple micro-colonisations from migrating NB cells. (B) A representative FFPE section of a PSCT with four IMR-32 colonies indicated (red borders). (C) IMR-32 colony surrounded by loose mesenchyme. LM = loose mesenchyme; NE = neural epithelium; C = cartilage; M = muscle; Blue arrows = vessels. Size bars: B:5mm, C:500μm.