pcbi.1007527.g005.tif (298.42 kB)
Median-Joining networks for samples of the CTB dataset annotated with pairwise distances.
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posted on 2019-12-09, 18:31 authored by Christine Jandrasits, Stefan Kröger, Walter Haas, Bernhard Y. RenardEdges between isolates with genetic distance of fewer than 10 SNPs identified in the original publication are labeled with SNP distances calculated with PANPASCO. Blue lines mark distances detected with PANPASCO, while gray ones mark original results. The comparison of these two analyses showed very similar results.
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pairwise SNP-distancepan-genome mappingtransmission surveillancedetectionMycobacterium tuberculosis transmission clusters Next-generation sequencingPANPASCOComputational pan-genome mappingsampleusageapproachwhole-genome sequencingdatasetpairwise distance methodintegral complementinvestigationdisease outbreaksscenariocharacteristicbase-by-base distance measuresanalysisMycobacterium tuberculosis lineagesreference genomesregion
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