pgen.1008055.g001.tif (874.24 kB)
Loss of function mutations in essential genes cause embryonic lethality in pigs - Fig 1
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posted on 2019-03-15, 17:39 authored by Martijn F. L. Derks, Arne B. Gjuvsland, Mirte Bosse, Marcos S. Lopes, Maren van Son, Barbara Harlizius, Beatrice F. Tan, Hanne Hamland, Eli Grindflek, Martien A. M. Groenen, Hendrik-Jan MegensA) Example of a carrier-by-carrier mating in Landrace. CxC litters will result in a 1:2 genotype ratio instead of the normal 1:2:1 genotype ratio. B) Fertility phenotypes for lethal recessives. A significant reduction in total number born (TNB) is observed for CxC compared to CxNC matings. C) Carrier frequency for lethal alleles in the period 2012–2018. Figure shows relative stable carrier frequencies over a time period of 6 years (except for LA4).
