Interaction effects of risk calculator score and negative stressful life events schedule (nSLES) score on whole-brain functional connectivity to bilateral amygdala during emotion processing (top).

Positive interactions between risk calculator score, nSLES score and activity were found within 2 clusters after correction for multiple comparisons. A graphical representation of this interaction in the right lateral occipital cortex is presented here (bottom). Higher risk calculator score showed a greater positive association between functional connectivity and nSLES score, which was not present at low risk calculator score. A full set of these interaction plots can be found in the supplementary. * au = arbitrary units All results were corrected for using Z-statistic threshold at z>2.3, pFWE<0.0017. A contrast of all emotions versus shape conditions was used. Functional connectivity values were mean adjusted using a healthy control sample.