Interaction effects of risk calculator score and negative stressful life events schedule (nSLES) score on whole-brain activity during emotion processing (top).

Positive interactions between risk calculator score, nSLES score and activity were found within 3 clusters after correction for multiple comparisons. A graphical representation of this interaction in the right fusiform gyri is presented here (bottom). Higher risk calculator score showed a greater positive association between activity and nSLES score. A full set of these interaction plots can be found in the supplementary. * au = arbitrary units All results were corrected for using Z-statistic threshold at z>2.3, pFWE<0.0017. A contrast of all emotions versus shape conditions was used. Activity values were mean adjusted using a healthy control sample.