Inhibition of NaChBac by lidocaine N-ethyl bromide.

(A) The voltage protocol used in this experiment. (B) 4 out of the 40 current traces from NaChBac channel recording before the drug treatment. (C) Average current trace. Black: before drug application (i.e. control); red: drug applied to the cis side of the bilayer; blue: drug applied to both sides; grey: drug removed from the cis side. Inset shows the chemical structure of lidocaine N-ethyl bromide.