Immunohistochemical staining of growth factors and quantitative analysis in aortic plaques from high cholesterol-fed rabbits.
(A) Protein expression of vascular endothelial growth factor A (VEGF-A), VEGF receptor 2 (VEGFR-2), basic fibroblast growth factor 2 (FGF-2), FGF receptor 1 (FGFR)-1, platelet-derived growth factor-BB (PDGF-BB) and PDGF receptor β (PDGFR-β). (Bars = 50 μm). (B–F) Quantification of VEGF-A, VEGFR-2, FGF-2, FGFR-1, PDGF-BB, and PDGFR-β. Data are presented as the mean±SEM. *p<0.05 vs. week 4; #p<0.05 vs. week 6; ^p<0.05 vs. week 8; &p<0.05 vs. week 10.