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Illustration of the relative zones of inhibition of screened compounds versus MU1140 and OG253.

2018-06-12T18:01:08Z (GMT) by Johan A. Kers Anthony W. DeFusco Jae H. Park Jin Xu Mark E. Pulse William J. Weiss Martin Handfield
<p>Controls are boxed in the upper-left corner and include blanks (Column 1, negative control), MU1140 (Column 2, positive control) and OG253 (Column 3, comparator).</p>

Categories

  • Biochemistry
  • Medicine
  • Microbiology
  • Pharmacology
  • Chemical Sciences not elsewhere classified
  • Ecology
  • Immunology
  • Biological Sciences not elsewhere classified
  • Information Systems not elsewhere classified
  • Mathematical Sciences not elsewhere classified
  • Cancer
  • Infectious Diseases

Keyword(s)

substitution variants performer OG 716 lantibiotic Mutacin 1140 fit-for-purpose lantibiotic vivo testing novel antibiotics novel lantibiotic infections Lantibiotics MU 1140-derived variants novel mechanism CDI hamster model CDAD 3 weeks post infection biologically-relevant systems

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