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Granulosa cells co-incubated with exosomes showed reduction in ROS level under oxidative stress or normal conditions compared to control ones.

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posted on 08.11.2017 by Mohammed Saeed-Zidane, Lea Linden, Dessie Salilew-Wondim, Eva Held, Christiane Neuhoff, Ernst Tholen, Michael Hoelker, Karl Schellander, Dawit Tesfaye

The ROS level (A) was measured under normal or oxidative stress conditions in granulosa cells co-incubated with exosomes released under normal (NormalExo) or stress (StressExo) conditions compared to groups cultured without exosomes. The ROS fluorescence intensity analysis (B). Data are mean ± SEM from four independent biological replicates. Bars with different letters showed statistically significant differences (p < 0.05).