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Selected copy number plots for chromosomes 6 and 17.

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journal contribution
posted on 2017-04-19, 17:39 authored by Verena Tiran, Stefanie Stanzer, Ellen Heitzer, Michael Meilinger, Christopher Rossmann, Sigurd Lax, Oleksiy Tsybrovskyy, Nadia Dandachi, Marija Balic

Depicted are segmented log2-ratio plots chromosome 6 and 17. The X- and Y-axes indicate the chromosome and the log2-ratios, respectively. Primary tumor, the unsorted primary cells, and the CD44-positive cells show very consistent copy number profiles. The high level gains on the long arm of chromosomes 6 and 17, respectively can also be observed in the ALDH-positive cell fraction, although with a much lower amplitude indicating a lower amount of tumor cells.

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