Fig 2.tif (1.16 MB)
Fold changes of microRNAs in pSS and SLE patients compared to controls.
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posted on 2017-03-24, 17:32 authored by Ji-Qing Chen, Gábor Papp, Szilárd Póliska, Krisztina Szabó, Tünde Tarr, Bálint László Bálint, Péter Szodoray, Margit Zeher(A) A total of 26 microRNAs (miRNAs) showed altered expression levels in patients with pSS compared to controls; among them, 14 miRNAs displayed more than 2-fold change. Expression of miR-150-5p was down-regulated in pSS. (B) All of these miRNAs were also analysed in patients with SLE and found to be elevated as well.
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miR -342. Expression levelslupus erythematosuscell lineage commitmentmiRNA expression profilesmiRNA expression levelsMicroRNA expression profiles8 pSS patientsB cell functionsdysregulated miRNA expression profilesB cell hyperactivitypSS patients 26 miRNAsB cell proportionsB cell distributionmiR -146a miR -16miR -223-5p miR -150-5p miR -155-5pIllumina next-generation sequencing technologySLE
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