Fig 4.tif (6.07 MB)
Expression of ANP32B in human HCC tissue.
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posted on 2017-05-09, 17:40 authored by Yoshinori Ohno, Mitsuhito Koizumi, Hironao Nakayama, Takao Watanabe, Masashi Hirooka, Yoshio Tokumoto, Taira Kuroda, Masanori Abe, Shinji Fukuda, Shigeki Higashiyama, Teru Kumagi, Yoichi Hiasa(A) Immunohistochemical staining of ANP32B in human HCC tissues (T) and non-tumor tissues (NT); the scale bar indicates a length of 50 μm. (B) Western blotting analysis of 3 patients with higher expression of ANP32B in T than in NT (tumor high ANP32B) and 2 patients with lower expression of ANP32B in T than in NT (tumor low ANP32B). (C) Levels of ANP32B mRNA in T and NT were compared individually. (D) Patients were divided into two groups by the T/NT ratio of ANP32B mRNA expression. Red bars represent the tumor low ANP32B group and black bars represent the tumor high ANP32B group. The cutoff value that divided the groups was 1.03.
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apoptosis-related proteinsphosphoprotein 32 family member BANP 32B knockdownANP 32B overexpressionANP 32B expressionpro-apoptotic agent staurosporineANP 32BRT-PCRUICCABTBcl -2 familyhepatocellular carcinomaANP 32B modulatestissueANP 32B expression plasmidsHCC cellsANP 32B mRNA expressionBax expressionHCC cell lines
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