Evaluation of rhodopsin (Rh) H1/H8 dimer row structure stability dependence on saturated lipid domain size.

(a) Averages of 〈S(t)〉_t over ten simulations, 〈S(t)〉 where the system consisted of only two H1/H8 dimers and various numbers of saturated and unsaturated lipids (S5 Fig). Error bars indicate standard deviations. 〈S(t)〉_t was the average time of S(t) between 50 to 100 μs and was evaluated according to the change in number of saturated lipids between two Rh-dimers. (b) Typical simulation snapshots at time (t) = 50 μs for several different numbers of saturated lipids (N_s = 0–7), where the saturated lipids were placed between parallel two Rh-dimers at t = 0 s (S5 Fig). At time (t) = 50 μs, two Rh dimers are disassembled mostly in the case of N_s = 0 and 1.