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Effects of topical PGA medication on rabbit IOP.

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posted on 2016-03-24, 06:46 authored by Xiaohong Li, Fen He, B’Ann T. Gabelt, Yun Wang, Suping Cai, Juanhui Cao, Ning Fan, Paul L. Kaufman, Xuyang Liu

Thirty μl of Lumigan (Bima, A) or Xalatan (Latan, B) was administered unilaterally to rabbit eyes (qd) for 5 consecutive days, i.e. at 0, 24, 48, 72, and 96 h; NS (control) was administered contralaterally. IOP was measured in a masked fashion using a TonoVet rebound tonometer immediately before each dosing, as well as 4 h and 8 h after dosing. The results were expressed as means±SD (n = 3). *, p<0.05, **, p<0.01, ***, p<0.001, compared with control by two-tailed paired Student’s t-test.

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