Fig 4.tif (371.65 kB)
Effect of a 5-day treatment with morusin (in mg/kg) on (A) interleukin 1β, (B) transforming growth factor β1, (C) superoxide dismutase and (D) catalase levels in TNBS-induced colitis, compared to the intact group, the untreated group (CTRL), and the group treated with sulfasalazine 50 mg/kg (SAS).
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posted on 2017-08-10, 18:10 authored by Zora Vochyánová, Marie Pokorná, Dominik Rotrekl, Václav Smékal, Petr Fictum, Pavel Suchý, Jan Gajdziok, Karel Šmejkal, Jan HošekValues were obtained from Western blot analysis, quantified by densitometry, and normalized to the β-actin level, as described in Materials and methods. Representative blots are shown. The results are expressed as the mean, with error bars representing SEM. CTRL vs. intact group: ## p < 0.01; CTRL vs. treated groups: * p < 0.05, ** p < 0.01, *** p < 0.001.
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MMP 2superoxide dismutasedosezymographic analysisTGF -β1 levelstissue damage scoresroot barkMorus albaTNBS-induced colitisrats Morusingrowth factorPrenylated flavonoid morusinanti-inflammatory agentsmgsulfasalazineWistar ratsSODIL -1β.Many studiesmatrix metalloproteinasesantioxidant enzymesMMP 9 activitiesprenylated flavonoidbowel disease
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