Effect of DA neurons and Meth stimulation on innate immune CCR5 transcription.

CCR5 gene transcription was examined in THP1 macrophages, treated with Meth or DA (1 uM), or co-cultured with SH-Sy5Y DA neurons, with or without a 1 hour pre-stimulation with Meth (60uM). Results normalized to the expression of GAPDH, represent the average ± SD of 2 experiments performed in quadruplicate. *p<0.05 in Bonferroni’s post hoc test.