pgen.1008435.g001.tif (2.41 MB)
Clustering analysis of FusA homologues.
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posted on 2019-10-15, 17:25 authored by Rhys Grinter, Pok Man Leung, Lakshmi C. Wijeyewickrema, Dene Littler, Simone Beckham, Robert N. Pike, Daniel Walker, Chris Greening, Trevor LithgowCLANS similarity network analysis identifies clusters of sequences in the FusA homologues identified by HMMER search of the UniProt reference proteomes dataset. Clusters are named based on the genus of a major species of origin for the cluster, with members of other prevalent genera listed. The presence of FusA sequences associated with the homologues of the protease FusC inside a cluster are noted, as is the most common lifestyle for bacteria in the cluster. Dots represent individual sequences and grey lines represent pairwise similarity relationships. An E-value cut-off of 1e-110 was used for clustering. A full list of sequences and metadata where available is provided in S1 Table.
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gene clustersGram-negative plant pathogensferredoxin uptake systemM 16 protease familyferredoxin processing protease FusCStructural analysisFusC shareFus homologues YddBgene cluster encoding proteinsuptake machineriesmembrane protein YddB sharesperiplasmic localisationplant hostsgenus Pectobacteriumprotein ferredoxinextracellular substrate binding siteEscherichia coliGram-negative bacteria BacteriaGram-negative bacteriaProtease-associated import systemsiron-dependent expressiontransport ferredoxinimport systemsmembrane ferredoxin transporter FusAPqqL
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