Fig 5.tif (774.11 kB)
COX-2/PGE2 regulates JAK2/STAT3 signaling in CRC cells.
figure
posted on 2015-05-08, 13:55 authored by Xuan Liu, Qing Ji, Naijing Ye, Hua Sui, Lihong Zhou, Huirong Zhu, Zhongze Fan, Jianfeng Cai, Qi LiA. and B. Extracts from SW620 and LoVo cells transfected with COX-2 over-expression or shRNA construct were analyzed for pJAK2, JAK2, pSTAT3, STAT3, MMP-2, MMP-9 and beta-actin. C. and D. Extracts from SW620 and LoVo cells treated with PGE2 for indicated durations were analyzed for pJAK2, JAK2, pSTAT3, STAT3, MMP-2, MMP-9 and beta-actin.
