Body weights, serum and renal biochemical determinations in mice with AAI-induced acute nephropathy.

<p>Animal model of nephropathy was performed in C57BL/6 mice. The mice were treated with AAI via intraperitoneal (i.p.) injection, and the accumulated AAI dosage was 45 mg/kg BW (15 mg/kg BW per day for 3 days). Five groups of 9 mice per group were used. Mouse body weights were recorded daily (<b>A</b>), changes in serum BUN and creatinine (<b>B</b>) levels, and urine protein and urine albumin <b>(C)</b> levels were determined. All values are expressed as the means ± SD of each group (n = 9). ** indicates <i>p</i> < 0.01 compared to the Control group; † and †† indicate <i>p</i> < 0.05 and <i>p</i> < 0.01 compared to the AAI group, respectively.</p>