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Axoneme formation and manchette removal is impaired in Drc7-/- testis.

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posted on 2020-01-21, 18:34 authored by Akane Morohoshi, Haruhiko Miyata, Keisuke Shimada, Kaori Nozawa, Takafumi Matsumura, Ryuji Yanase, Kogiku Shiba, Kazuo Inaba, Masahito Ikawa

Immunofluorescence analysis of spermatids from Drc7+/- and Drc7-/- mice. α-tubulin (green) stains both manchette and axoneme. Elongating spermatids are shown progressively from left to right. Arrows indicate axoneme. Axoneme formation is severely impaired in Drc7 KO spermatids. An arrowhead indicates abnormal caudal movement of the manchette. Hoechst (blue), nucleus. Scale bar, 10 μm.

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